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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b458ced12d45f8977792b0eb50d376bfb23b175f7d962a3a53885795a5dabf5' 
  AND token = '75U9QtRnWrKBKTlYzp8378Tw7X9F9dZ9JeaPrzRsafA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}