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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a06340327419a3a2c6b7d8d8430c1c2e6ad0c8d0d1087bc4684a46139d97c05' 
  AND token = 'ZNINlqyuiUEDl55e3jPNd3d6vJR4AGWFw2oVV3LXNLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}