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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e33e6f078d907c2f6b5aef4e02fd63db7048d9a8c7e91477eb98812d894d5f9' 
  AND token = 'yN9apL2WNoqOWOdw4AI4zH/qd6wFB5bzuwvaMNqHKm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}