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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '567230818d9543df538f659317b04a5dcffa76eb6f8693444c1608b476689c96' 
  AND token = 'LsIxSUM/zhaS7WeMtBwGw0aIaGetWYWk8+avQyz4c9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}