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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ce1dbe01f96a28e19af69829f30c2bd21f2fc37bc2f7b7c1177ab47e04fdab' 
  AND token = 'ofJiNeatsemhJ890hFm+oabOy7NMx0PaHLmxLFctw2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}