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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb2be5faa69ed7e871dd2795126eebcff01c0ac01067a095010e5f1c7a3e38d0' 
  AND token = 'B2rjhZK/tsQ+ZfkFzYXzfOj0b2lFuBo/CKKYKzjQjE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}