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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d0d36de39ee86354a2e4f51c2cff43dc29ed77a46db2c864ad2a615d36270c' 
  AND token = 'GcNKxlDjCwtBdpynHLdpAiVnCfv3nKVK3QdkGfhaRYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}