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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8db01a52f52a7cfd1053747ac4aadd4866aa1e981725c2d2c3a23b6aa7e8e27' 
  AND token = 'BMd5mrxVo+WqrPkU4cDmydMMjPh8/DBckpmxW0/vUew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}