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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd03439b900139f547db8e12abad764d09197d280f3e1e3e69b1bc9010e2be997' 
  AND token = 'ffiNOPHxiqYnTH5HEfRmycwCg6JEp+7+wq6eq1AgPxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}