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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1f6e484f06c4b885b5fac62548ffeeda6e4fa945d3c12e3390ef340af59b49' 
  AND token = 'GuePzqeUS2LRcI+kO9k9u1QRTJA7pFU41HdYLgxgUxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}