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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0a3f28c582c74708d7c0bc4a695fc27df56a9e7af12ff33f18c3ec5cbcb752' 
  AND token = 'V1rF76fhmv1JO4tMYWgLJUmb45ch1HsAIsilgu0AFXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}