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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0079f8dd4d94d43fd24e5c391f8f722c3fc5f1afb78011f8cc9f14f728e13f24' 
  AND token = 'MF9wacMDAYgjyn2q58QZZxGRxFQ/bmH77CBLhOyQvrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}