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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e56636ed2c177f0535e0d2c85214c7b29e1e0bd2aab6cf5a4654f6fa88da468a' 
  AND token = 'zMick5YTG0qWx+Dd1oNSV4oOwgCZetQ6/lXfO7H5DSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}