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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379bb7a17a0063b90eb1b52fd8951a30b920b2446fa483e0340f90ba28e50845' 
  AND token = 'r9MC+Jg1V2w64auvdlW7c7VskHCjSCfgq6A90zrTeyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}