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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486075845f9fc57b0920ca5e3cd47dbe33440f832416bcc202ff65e9d0599c1b' 
  AND token = 'CL+H9LEZ6sNHm4TPp+ruc47P8PRrJMnUJKICesKqe5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}