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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d14b2f93e35e2e0f696dd1153d446f52bee2a0ee49d1c31f0273eba4db93161' 
  AND token = 'fMJgQJvq0b29H6qn4v8lG/FWPrG+nItrS6uzcvLqF8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}