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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327cda011184abc21d2d02a9a5a6ff44ac98871296f0b60b3e79f981feb0384a' 
  AND token = 'U5xSpsUeHNi16byCh0/H7JYfwege93fEItZ1su8HgIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}