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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d79e2fd8dd86b25c7b31ae955d8e7cca4465a268edb4d5307652640bcbf877e' 
  AND token = '21uG+XJKN6/kbKe38+PCDshMql2MEaY365a4akXoxf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}