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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b114d6c6ac9a4d04ede1d060d1f0d7b73a2cbe52abba4951e5380a96c797e321' 
  AND token = 'Ein8Vtq/rOCf/jEp4TFDXE+BOXeCVWFXMdUdDzgVYP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}