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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '413b2ba8c49a371f74fb71ba626e2b196c14a043f94a75859b1d74ab17ae4b61' 
  AND token = '77kQUKPrZwtVVEhcFks/rZs+IhzjT7UxitO9LL/jP9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}