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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02ef49464df1034baa5a30768b0970617263550294011d531c6541bbcd3b2694' 
  AND token = 'HnLcb3Zh2z9p+HD9kkyhehG9syhxMfEq4+Y+NeZgbqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}