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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e113cb3d9804eb8fac2aaac19911a2751b21c18d92c293ebdeec746de2c9cf00' 
  AND token = 'qOifPOoFd75zPaUnIUEB2Wrx2IyTrXIptTxodBeYNVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}