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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc8c12a1879778851259a87c1660833e6f7978b845aaea042a80a1abe0af464' 
  AND token = 'fc2tIEpbjxHPe8VRzcEXZ5/FqF5yRLCxHvIMzqgK+1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}