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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '067f1bb7a8e9450826c80e071d609e2e6d791e3e3377ebd95394876c0c163629' 
  AND token = 'uSfezJzIUNwGtdaP+QEBrm91PI97nc98LghJzu8wcEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}