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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '843df7f2180d66a3f7fb3b6e5ad47b0aa21737427b8feec2d06e4d6c8fe3461c' 
  AND token = '7HuLaLqYxMBZ9ZZ/oPMcoXFRMPx2enPCdT/tAedJUfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}