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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1151ddc399a0d9beefdd08aecb8d235e1b3d1ac75a537443935aa71dc4ac1d97' 
  AND token = 'eBuQqYY7n5kHWUo7mFFY7I5HBarIQcqrVrQsZ4RIgO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}