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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f86a342f7184ca4b9aa2db52a201a182bb1421a53d88e383fdf1ddef6e324b3' 
  AND token = 'tqiLgd1v641I4AbQl4t+1mb3095/Ce2VSl2ZtvWacTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}