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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b890801aa4237580dd6d2fbeb6b92445d0b09b27aa851279bd3bd7b4bf48207' 
  AND token = 'kWn0XCxu5EwDdsoSZzgk3+CNDjiOf/lc78J1hfd2fKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}