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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '052bc229345dcacce5f93c28ff42d25f15f0803721e26847301cbb4c77bf3f65' 
  AND token = 'DIKVM+5/a2fkMhi+pNCgAijXDjYsWeGyGUNEF3C2cdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}