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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c77578e866a07cefa7fb37d8fcd69ba99771c5bc0d7e13aa7c8c90e7cfe227b' 
  AND token = 'ayW971aImSxukwi+wMPDYN0uP7qR+r+4hIrTOmQADRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}