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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca064ba3dadfccdfce673e2906bc825b73f0fa8dd47628b1918f7aece6af2b6' 
  AND token = 'hOmtzYJ87lf91yS3SfdbgpNnTkEW1wfWLjKvSwJeAI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}