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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4eba18b5d68b5b8278618ee4b8693b115237d8a1a52d561832246f06cac45e' 
  AND token = 'wJbZWSp6YdIEmT7qkz3AqG8gieRS8aMDVtQg4YTdeTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}