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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c58447860a9a2ee318219fb8714ae46a0dd1d45b9f2c19206305e521c0fc6c6' 
  AND token = 'oD5FmdN50td6inPfdbISm0EfmUyiAWk2SBgWsMTe/Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}