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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c41ac64a7701b1800fd00c65b2616916341055bb3c711b7d3b1a89028edc7f2' 
  AND token = 'DtFD8Wkik0hY1UzeBDRWcUogfBiB7uZuAb9qZu074W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}