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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bf656b5429a7e0fd64e5d08ca25b0436f1ad5c3adb09ec8747fe51d3c26406d' 
  AND token = 'HsToAg1OK7YAZI2YST86nfbv8Zw3/Vftxphi+Z7+eEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}