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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28a594a0ecc90d832362ab0f621a31c3d68398769950789493b639c86e3f3e51' 
  AND token = 'PY1/UtRa3HDwf3BTqF4NT9Mb2r8qnE5fyW44g7w4XA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}