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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b21cd24b3bd8c566c0c00df201664d8f89b7487b356cea86f63b6f14a5abd397' 
  AND token = 'bEoqgRnIx+bMpi9Ji+/ypiSq/YYr2q2LlrgS0snqIAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}