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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6829be49f29621725b3cf779a567d079d72a89dab0bcb3b0829f58f5c6d75ab7' 
  AND token = 'WQnDuiTofPUU2Yx1CY+zHnpj0cS51uHUGr9bf/fwE48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}