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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c2e3269f37a0dcdc024dd127c0c4c0f353b4ff2293fb92f53415355dc33f2f' 
  AND token = 'qjMBl9Q1QEjzXFdoKGVxLgRclt2uuBgnuZAaLBeMkdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}