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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc0727be22e99235c098a6e80e3f55cc53c8c11f7c1b8fd21234adbec28e2d9f' 
  AND token = 'wehJdLmhIZY77uE/WFFbIW8rTaZaEpWcgWwj0Sml2Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}