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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0278d7bbaa7550a2faf83b10b46ba260a5ec85e4513386632f652d9574bb8836' 
  AND token = 'ln2QL2zqhL1zcjNFKDf4CsxZkOkj6a0yiQwygqyiIOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}