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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46e8ca4a763e86a9873eb8f8780e6375e89d9fa73dcca6d34b74a183412958c' 
  AND token = 'Nk7CnQrJobF1IAgUY5dpTmKtzagk9ASUV+WZarDTSVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}