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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19449eb09c1a569a46f716b58c4f6a65215240ac8e04aad2c5566b42b60fb676' 
  AND token = 'l9tu83RRZfUKI3PWgcrMsSfAgDx3PQ3kIGR3G+dQvsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}