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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86182d1b58e1518df5a18e76f7b2a5873028ee386311b563597e14dda105e2df' 
  AND token = '818RESnyYpnXweHQ45E86ma3dbmMmLUx+jo3mKoUC28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}