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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f03164eac996c51ef729e647cdde664dc11c7e08144adfe3fa9db76e6c8cf6ce' 
  AND token = 'D6sfGrdKB/V+L1ZRDOYB50TMU2EN/V29BwPtGBCbm+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}