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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c594f36b807910a2b1e125c84596b7df46df17b7a33169afc7c0cc41fec9121a' 
  AND token = 'bDeMXQ700v4XqiQPokpczQTJQZd8VvRgMHxFPuA2wkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}