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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36d8ad010ecf326f58fa3939a0d0bc35df5970c499b397e373787e81b151fbf1' 
  AND token = '5C9V+WKJtybyAOCEGt7PV8iphjFPdObUkxtp9OBVL2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}