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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59b9786b76e421e77c3a36249f09b3765a78afc3c9955606c5ae596931b867f2' 
  AND token = 'ZHbSqI96fpr8T3fxqFX0F1eUcUsDkL1vMxgTlj86DBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}