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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0601a5283de5611afd2f05717c85106f3530c6055e159cd54d6d07ebdb009e4a' 
  AND token = 'xf5MsRrSrwvNBRB5fSIxmHSYsRWAtYpqQ5pty0+IWlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}