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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8001115bf25d471acd69edc92de45afed9955d6baf15d9167b86c35ca0cc4f0a' 
  AND token = 'KB5n2QTHiI4+Rqs4+6+MhmpgOm7fl2f4LJQ/tnGJDCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}